Eufemia Tufano undertook her musical studies at Conservatoire of Salerno, where she graduated. Eufemia Tufano specialized in baroque music with Maestro Antonio Florio, at the Conservatoire of San Pietro

Eufemia Tufano debuted in 2000, when she sang in Cinderella in Siena, and Le jongleur de Notre-Dame in the opening season at Opera di Roma, under the conduction of Gianluigi Gelmetti. Eufemia Tufano sang